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Zh Vyssh Nerv Deiat Im I P Pavlova. 2007 May-Jun;57(3):336-43.

[Typological characteristics of behavior in strains of rats bred for enhancement and absence of pendulum movements. Association with brain monoamines].

[Article in Russian]

Abstract

Typological characteristics of behavior were studied in rats bred for enhancement (PM+) and absence (PM-) of pendulum movements. Excitement in different test situations was manifest in PM+ rats, whereas passive defensive reactions were characteristic of PM- rats. Increased excitability of PM+ rats was expressed in their greater predisposition to audiogenic epilepsy (83% in PM+ versus 40% in PM- rats). On the contrary, PM- rats were found to be more prone to freezing (61% in PV- versus 11% in PM+). In PM+ rats, noradrenaline and serotonin contents were decreased in hypothalamus (as compared to PM- and control Wistar stain), whereas in PM- rats, serotonin content was increased in striatum, hypothalamus and midbrain as compared to control strains.

PMID:
17642375
[Indexed for MEDLINE]

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