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Cell Oncol. 2007;29(4):269-77.

BRAF in papillary thyroid carcinoma.

Author information

1
Istituto Tumori Giovanni Paolo, Bari, Italy.

Abstract

Novel genetic findings about papillary thyroid carcinoma identify BRAF gene as a subject of great interest. Involvement of BRAF gene in pathogenesis of PTC, diagnostic value and the putative prognostic significance of its T1799A mutation are summarized in this article. Furthermore, a particular attention is focused to the role of pre-operative detection of BRAF mutation in the FNAB specimens of thyroid nodules and to the use of this gene as target for an effective cancer therapy.

PMID:
17641411
PMCID:
PMC4618204
[Indexed for MEDLINE]
Free PMC Article

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