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Neuropsychiatr. 2007;21(2):121-30.

[Lithium and bipolar disorder--a renaissance?].

[Article in German]

Author information

1
Aƶ Krankenhaus Neunkirchen. www.simhandl.at

Abstract

OBJECTIVE:

Overview and discussion regarding the use and relevance of lithium as an therapeutic agent for bipolar disorder in general, with a special focus on pregnancy, suicidality and possible side-effects.

METHOD:

Literature was handsearched and by searches of medline with special interest in recent results and comparative studies.

RESULTS:

Lithium is still of high importance in the treatment of bipolar disorder. It is unmatched regarding decades of clinical experience and scientific evidence. It has a proven efficacy in every spectrum of bipolar illness, with less profound data regarding acute bipolar depression. Especially long term treatment of bipolar patients with lithium shows clear clinical benefits i.e.: importance of a continuous setting, gain of mood stabilizing effect over time, no loss of efficacy, reduced morbidity and mortality.

DISCUSSION:

Lithium should be regarded as a first line treatment for bipolar disorder.

PMID:
17640498
[Indexed for MEDLINE]
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