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Cell. 2007 Jul 13;130(1):16-8.

RNA polymerase II: just stopping by.

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1
Department of Medical Genetics, University of British Columbia, Vancouver, BC V6T 1Z3, Canada. mlorincz@interchange.ubc.ca

Abstract

In this issue of Cell, Guenther et al. (2007) analyze the presence of chromatin marks and RNA polymerase at transcription start sites in the human genome. Their results reveal that many "inactive" genes harbor histone marks associated with active transcription at their 5' ends and that although these genes initiate transcription, they do not generate full-length transcripts.

PMID:
17632051
DOI:
10.1016/j.cell.2007.06.040
[Indexed for MEDLINE]
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