Chemical implementation of neural networks and Turing machines

Proc Natl Acad Sci U S A. 1991 Dec 15;88(24):10983-7. doi: 10.1073/pnas.88.24.10983.

Abstract

We propose a reversible reaction mechanism with a single stationary state in which certain concentrations assume either high or low values dependent on the concentration of a catalyst. The properties of this mechanism are those of a McCulloch-Pitts neuron. We suggest a mechanism of interneuronal connections in which the stationary state of a chemical neuron is determined by the state of other neurons in a homogeneous chemical system and is thus a "hardware" chemical implementation of neural networks. Specific connections are determined for the construction of logic gates: AND, NOR, etc. Neural networks may be constructed in which the flow of time is continuous and computations are achieved by the attainment of a stationary state of the entire chemical reaction system, or in which the flow of time is discretized by an oscillatory reaction. In another article, we will give a chemical implementation of finite state machines and stack memories, with which in principle the construction of a universal Turing machine is possible.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Animals
  • Mathematics
  • Memory
  • Models, Chemical*
  • Models, Neurological
  • Neural Networks, Computer*
  • Neurons / physiology