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Appl Physiol Nutr Metab. 2007 Aug;32(4):770-7.

Bones and beyond: an update on the role of vitamin D in child and adolescent health in Canada.

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1
Program in Human Nutrition, Department of International Health, The Johns Hopkins Bloomberg School of Public Health, 615 N. Wolfe St., Room W2041, Baltimore, MD 21205, USA. droth@jhsph.edu

Abstract

Knowledge regarding the physiological role and dietary requirements of vitamin D has dramatically expanded over the past several decades. The "new" vitamin D is not only a mediator of calcium homeostasis, but also has important immunomodulatory, anti-microbial, and anti-proliferative actions. Amidst the growing interest in vitamin D as a mediator of many chronic diseases of adulthood such as cancer and type II diabetes, less attention has focused on the implications of the new understanding of vitamin D for child and adolescent health. This article reviews the definition of vitamin D insufficiency (VDI) as it applies to children and adolescents, the current vitamin D status of Canadian children and adolescents, pediatric conditions that may be related to VDI, and the evidence base for current dietary recommendations for vitamin D intake. Pharmacokinetic studies and epidemiologic research that incorporates clinical and functional outcomes are needed to clarify the role of vitamin D in growth and development and the specific dietary vitamin D requirements among Canadian children and adolescents.

PMID:
17622292
DOI:
10.1139/H07-055
[Indexed for MEDLINE]
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