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Am J Geriatr Cardiol. 2007 Jul-Aug;16(4):243-8.

Long-term follow-up of very old heart failure patients enrolled in a trial of exercise training.

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Section of Ageing and Health, University of Dundee, Ninewells Hospital, UK.


Little is known about how physical and psychological status changes with time in older heart failure patients. The authors followed up a cohort of 82 patients (mean age, 80.5 years) enrolled in a randomized controlled trial of exercise training in heart failure. Six-minute walk test, accelerometry, functional status, quality of life, anxiety, and depression were measured at baseline, 3 months, 6 months, and a mean of 19 months post-enrollment. There were no significant differences between the exercise and control groups at long-term follow-up. Six-minute walk distance declined by only 0.2 m/month in those attending final follow-up (vs 4.6 m/month in nonattenders; P=.03). Similar results were seen for other outcomes. Only a small proportion of the variance in change of any of the outcomes was explained by differences in baseline variables.

[Indexed for MEDLINE]

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