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BJOG. 2007 Sep;114(9):1079-87. Epub 2007 Jul 6.

Effects of interpregnancy interval and outcome of the preceding pregnancy on pregnancy outcomes in Matlab, Bangladesh.

Author information

1
Labor and Population Program, The RAND Corporation, Santa Monica, CA, USA. julie@rand.org

Abstract

OBJECTIVE:

To estimate the effects on pregnancy outcomes of the duration of the preceding interpregnancy interval (IPI) and type of pregnancy outcome that began the interval.

DESIGN:

Observational population-based study.

SETTING:

The Maternal Child Health-Family Planning (MCH-FP) area of Matlab, Bangladesh.

POPULATION:

A total of 66,759 pregnancy outcomes that occurred between 1982 and 2002.

METHODS:

Bivariate tabulations and multinomial logistic regression analysis.

MAIN OUTCOME MEASURES:

Pregnancy outcomes (live birth, stillbirth, miscarriage [spontaneous fetal loss prior to 28 weeks], and induced abortion).

RESULTS:

When socio-economic and demographic covariates are controlled, of the IPIs that began with a live birth, those < 6 months in duration were associated with a 7.5-fold increase in the odds of an induced abortion (95% CI 6.0-9.4), a 3.3-fold increase in the odds of a miscarriage (95% CI 2.8-3.9), and a 1.6-fold increase in the odds of a stillbirth (95% CI 1.2-2.1) compared with 27- to 50-month IPIs. IPIs of 6-14 months were associated with increased odds of induced abortion (2.0, 95% CI 1.5-2.6). IPIs > or = 75 months were associated with increased odds of all three types of non-live-birth (NLB) outcomes but were not as risky as very short intervals. IPIs that began with a NLB were generally more likely to end with the same type of NLB.

CONCLUSIONS:

Women whose pregnancies are between 15 and 75 months after a preceding pregnancy outcome (regardless of its type) have a lower likelihood of fetal loss than those with shorter or longer IPIs. Those with a preceding NLB outcome deserve special attention in counselling and monitoring.

PMID:
17617195
PMCID:
PMC2366022
DOI:
10.1111/j.1471-0528.2007.01338.x
[Indexed for MEDLINE]
Free PMC Article

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