Format

Send to

Choose Destination
See comment in PubMed Commons below
Ultrastruct Pathol. 2007 May-Jun;31(3):241-7.

Clear-cell ependymoma of the cerebellum: a case report.

Author information

1
Department of Pathology, Seoul National University College of Medicine, Seoul, Republic of Korea.

Abstract

A case of clear-cell ependymoma occurring in the cerebellum of a 3-year-old girl is reported. Light-microscopically, the tumor consisted mainly of clear cells with a perinuclear halo and showed some vague perivascular pseudorosettes, not true rosettes. In addition, the histological features of anaplasia, characterized by increased mitosis and focal pseudopalisading necrosis, were also observed. Immunohistochemically, the tumor cells were focally positive for glial fibrillary acidic protein and weakly positive for epithelial membrane antigen. Ultrastructurally, the intermediate junctions and rudimentary cilia confirmed the ependymal differentiation. Fifteen cases of infratentorial clear-cell ependymoma have been reported to date, and this case is the second childhood tumor among them, to the best of the authors' knowledge.

PMID:
17614003
DOI:
10.1080/01913120701446841
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Taylor & Francis
    Loading ...
    Support Center