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Clin Rehabil. 2007 Jun;21(6):511-22.

Frailty modifies effectiveness of psychosocial intervention in recovery from stroke.

Author information

1
Department of Society, Human Development, and Health, Harvard School of Public Health, Boston, MA 02115, USA.

Abstract

OBJECTIVE:

To evaluate the impact of a psychosocial intervention on instrumental activities of daily living, physical performance, cognition and mortality after stroke.

DESIGN:

A randomized clinical trial.

SETTING:

Patients were recruited from hospitals and rehabilitation centres; the intervention took place in subjects' homes.

SUBJECTS:

Two-hundred and ninety-one stroke survivors over age 45. One-hundred and forty-six subjects were assigned to the intervention and 145 subjects were assigned to usual care.

INTERVENTION:

Up to 16 meetings conducted over six months in the patient's home (approximately weekly for 12 weeks, followed by tri-weekly sessions for another 12 weeks). Sessions lasted approximately 1 hour and included, when possible, the entire support system (stroke survivor, primary caregiver, additional family and friends, and professional caregivers).

MAIN OUTCOME MEASURES:

Instrumental activities of daily living, physical performance, and cognition were assessed six months post stroke; mortality was assessed at an average of 47 months post stroke.

RESULTS:

No significant differences in outcomes were observed between the intervention and usual care groups when analysing the total study population. Among non-frail participants (n = 156), subjects randomized to treatment had better scores on instrumental activities of daily living (mean score among treated = 12.4 (standard deviation (SD) = 2.1), mean score among usual care subjects = 11.3 (SD = 2.9), P-value for difference in means = 0.01) and reduced risk of mortality (P = 0.03) than subjects randomized to usual care.

CONCLUSION:

While there is evidence that the treatment benefited healthier subgroups, results also show evidence that the treatment was not effective, and possibly harmful, in frail subgroups.

PMID:
17613582
DOI:
10.1177/0269215507078312
[Indexed for MEDLINE]
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