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Nat Rev Mol Cell Biol. 2007 Aug;8(8):603-12.

Pathways of clathrin-independent endocytosis.

Author information

1
National Centre for Biological Sciences, UAS-GKVK Campus, Bangalore 560065, India. mayor@ncbs.res.in

Abstract

There are numerous ways that endocytic cargo molecules may be internalized from the surface of eukaryotic cells. In addition to the classical clathrin-dependent mechanism of endocytosis, several pathways that do not use a clathrin coat are emerging. These pathways transport a diverse array of cargoes and are sometimes hijacked by bacteria and viruses to gain access to the host cell. Here, we review our current understanding of various clathrin-independent mechanisms of endocytosis and propose a classification scheme to help organize the data in this complex and evolving field.

PMID:
17609668
DOI:
10.1038/nrm2216
[Indexed for MEDLINE]

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