Format

Send to

Choose Destination
Cell. 2007 Jun 29;129(7):1249-50.

Need for speed: mechanical regulation of a replicative helicase.

Author information

1
Department of Physics and Institute for Genomic Biology, University of Illinois, Urbana-Champaign, and Howard Hughes Medical Institute, Urbana, IL 61801, USA. tjha@uiuc.edu

Abstract

There is much debate about how helicases unwind DNA during DNA replication and how their activity is regulated. In this issue, Johnson et al. (2007) shed light on this conundrum using a single molecule approach to dissect the behavior of the T7 DNA helicase.

PMID:
17604712
DOI:
10.1016/j.cell.2007.06.007
[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center