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Am J Pathol. 2007 Aug;171(2):375-85. Epub 2007 Jun 28.

A perspective on DNA microarrays in pathology research and practice.

Author information

1
Department of Pathology, Stanford University School of Medicine, CCSR-3245A, 269 Campus Dr., Stanford, CA 94305-5176, USA. pollack1@stanford.edu

Abstract

DNA microarray technology matured in the mid-1990s, and the past decade has witnessed a tremendous growth in its application. DNA microarrays have provided powerful tools for pathology researchers seeking to describe, classify, and understand human disease. There has also been great expectation that the technology would advance the practice of pathology. This review highlights some of the key contributions of DNA microarrays to experimental pathology, focusing in the area of cancer research. Also discussed are some of the current challenges in translating utility to clinical practice.

PMID:
17600117
PMCID:
PMC1934527
DOI:
10.2353/ajpath.2007.070342
[Indexed for MEDLINE]
Free PMC Article
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