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Bioinformatics. 2007 Sep 1;23(17):2337-8. Epub 2007 Jun 28.

POODLE-S: web application for predicting protein disorder by using physicochemical features and reduced amino acid set of a position-specific scoring matrix.

Author information

  • 1Computational Biology Research Center, National Institute of Advanced Industrial Science and Technology, 2-42 Aomi, Koto-ku, Tokyo 135-0064, Japan. poodle@cbrc.jp

Abstract

Protein disorder is characterized by a lack of a stable 3D structure, and is considered to be involved in a number of important protein functions such as regulatory and signalling events. We developed a web application, the POODLE-S, which predicts the disordered region from amino acid sequences by using physicochemical features and reduced amino acid set of a position-specific scoring matrix.

AVAILABILITY:

POODLE-S is available from http://mbs.cbrc.jp/poodle/poodle-s.html and can be used by both academic and commercial users.

PMID:
17599940
DOI:
10.1093/bioinformatics/btm330
[PubMed - indexed for MEDLINE]
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