The incidence of vitiligo at King Khalid University Hospital (KKUH), Riyadh, Saudi Arabia was 2.5% for the period from 1985-1990. The majority (96.1%) were Saudis. Approximately 64% were below the age of 30 years and the average was 25.6+/- SD 13.7 years. Fifty-six percent of the patients were males and 43% were females. More than half of the patients had the lesions for a period between one and nine years and 17.17% had them for more than 15 years. Only 12% had a positive family history of vitiligo. The majority (54%) of the lesions were in exposed areas. The associated diseases with vitiligo are also reported. It appears that the clinical pattern of vitiligo is not different from what is reported in other studies.