Atmospheric pressure ionization permanent magnet fourier transform ion cyclotron resonance mass spectrometry

J Am Soc Mass Spectrom. 2007 Aug;18(8):1552-8. doi: 10.1016/j.jasms.2007.05.010. Epub 2007 May 23.

Abstract

A new Fourier transform ion cyclotron resonance mass spectrometer based on a permanent magnet with an atmospheric pressure ionization source was designed and constructed. A mass resolving power (full-width-at-half-maximum) of up to 80,000 in the electron ionization mode and 25,000 in the electrospray mode was obtained. Also, a mass measurement accuracy at low-ppm level has been demonstrated for peptide mixtures in a mass range of up to 1200 m/z in the isotopically resolved mass spectra.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Algorithms
  • Atmospheric Pressure
  • Peptides / chemistry*
  • Spectrometry, Mass, Electrospray Ionization / instrumentation*
  • Spectrometry, Mass, Electrospray Ionization / methods
  • Spectroscopy, Fourier Transform Infrared / instrumentation*
  • Spectroscopy, Fourier Transform Infrared / methods

Substances

  • Peptides