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Circ Res. 2007 Jun 22;100(12):1686-95.

Role of Krüppel-like transcription factors in endothelial biology.

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  • 1Cardiovascular Research Institute, Case Western Reserve University, Cleveland, OH 44106, USA.


Krüppel-like factors are members of the zinc finger family of transcription factors that have been implicated as playing key roles in regulating cellular differentiation and tissue development. Studies over the past several years support an important role for this family of factors in vascular biology. This review summarizes the role of Krüppel-like factors in endothelial cell biology.

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