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Mini Rev Med Chem. 2007 Jun;7(6):559-69.

Allosteric enhancers for A1 adenosine receptor.

Author information

1
Dipartimento di Scienze Farmaceutiche, Università di Ferrara, Ferrara, Italy. baraldi@unife.it

Abstract

Allosteric enhancers at the adenosine A(1) receptor have received attention as anti-arrhythmic cardiac agents, and, more recently, as anti-lipolytic agents. In addition, allosteric modulators at the adenosine A(1) receptor have therapeutic potential as analgesics and neuroprotective agents. In particular, the compounds with improved potency as enhancers and reduced antagonist properties are mentioned.

PMID:
17584155
DOI:
10.2174/138955707780859459
[Indexed for MEDLINE]

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