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Curr Med Chem. 2007;14(13):1459-77.

Dual action-based approaches to antibacterial agents.

Author information

1
Department of Chemistry, University of Wollongong, Wollongong, NSW, 2522, Australia. john_bremner@uow.edu.au

Abstract

This review collates and analyses recent work done on dual action approaches to tackling the mounting health problem of resistance by human pathogenic bacteria to antibacterial agents. In particular the areas reviewed include the use of two drugs in combination, dual action prodrugs, and dual action drugs (or hybrid drugs).

PMID:
17584056
DOI:
10.2174/092986707780831168
[Indexed for MEDLINE]

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