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Antimicrob Agents Chemother. 2007 Sep;51(9):3388-90. Epub 2007 Jun 18.

High prevalence of metallo-beta-lactamase and 16S rRNA methylase coproduction among imipenem-resistant Pseudomonas aeruginosa isolates in Brazil.

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1
Division of Infectious Diseases, University of Pittsburgh Medical Center, Falk Medical Building Suite 3A, 3601 Fifth Avenue, Pittsburgh PA 15213, USA. doiy@dom.pitt.edu

Abstract

Rates of metallo-beta-lactamase and 16S rRNA methylase production were investigated in 51 imipenem-resistant Pseudomonas aeruginosa clinical isolates collected from hospitals in São Paulo, Brazil. Of them, 57% and 75% produced SPM-1 and RmtD, respectively. Of note, 51% produced both enzymes, suggesting that their coproduction is already common in this geographic area.

PMID:
17576840
PMCID:
PMC2043184
DOI:
10.1128/AAC.00443-07
[Indexed for MEDLINE]
Free PMC Article
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