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Arch Soc Esp Oftalmol. 2007 Jun;82(6):377-80.

[Response to idebenone and multivitamin therapy in Leber's hereditary optic neuropathy].

[Article in Spanish]

Author information

1
Hospital Universitario de Bellvitge, L'Hospitalet de Llobregat, Barcelona, España. noebg76@hotmail.com

Abstract

OBJECTIVE:

To ascertain the efficacy of idebenone and multivitamin treatment in Leber's hereditary optic neuropathy (LHON).

METHOD:

Two patients diagnosed of unilateral LHON were treated with megadoses of idebenone, vitamin C and riboflavin for one year. They were examined clinically before, during and after treatment.

RESULTS:

No improvement of visual function was observed. Despite the idebenone treatment, in both cases the second eye became involved.

CONCLUSIONS:

Despite previous reports of visual recovery with idebenone in patients with LHON, our experience shows that an effective treatment for Leber's disease remains to be found.

PMID:
17573650
[Indexed for MEDLINE]
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