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Nat Rev Mol Cell Biol. 2007 Jul;8(7):542-51.

Drosophila melanogaster embryonic haemocytes: masters of multitasking.

Author information

  • 1Department of Biology and Biochemistry, University of Bath, BA2 7AY, UK. w.wood@bath.ac.uk

Abstract

Drosophila melanogaster haemocytes constitute the cellular arm of a robust innate immune system in flies. In the adult and larva, these cells operate as the first line of defence against invading microorganisms: they phagocytose pathogens and produce antimicrobial peptides. However, in the sterile environment of the embryo, these important immune functions are largely redundant. Instead, throughout development, embryonic haemocytes are occupied with other tasks: they undergo complex migrations and carry out several non-immune functions that are crucial for successful embryogenesis.

PMID:
17565363
DOI:
10.1038/nrm2202
[PubMed - indexed for MEDLINE]

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