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Infect Control Hosp Epidemiol. 2007 Jul;28(7):892-5. Epub 2007 May 31.

Review of clinical trials of skin antiseptic agents used to reduce blood culture contamination.

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  • 1Division of Infectious Diseases, University of Michigan Medical School, Ann Arbor, MI, USA. malanian@med.umich.edu

Abstract

False-positive blood culture results may lead to prolonged hospitalization, inappropriate antibiotic administration, and increased healthcare costs. We conducted a review of the literature to assess the effect of skin antiseptic agents on the rate of false-positive blood culture results. We found no clear evidence to suggest which antiseptic should be used to prevent false-positive results. Studies suggest, however, a possible benefit from the use of prepackaged skin antiseptic kits and alcohol-containing antiseptics.

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