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Cancer Genet Cytogenet. 1991 Oct 15;56(2):243-53.

Partial trisomy 1q. A nonrandom primary chromosomal abnormality in myelodysplastic syndromes?

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1
Institut für Humangenetik, Medizinische Universität zu Lübeck, Germany.

Abstract

Cytogenetic and clinical data of 11 patients with de novo myelodysplastic syndromes and partial or total trisomy of the long arm of chromosome 1 are presented. In eight of these patients trisomy 1q was the sole karyotypic change and therefore can be classified as a primary chromosome anomaly. A remarkably young median age of 36.5 years was noticed in this patient group.

PMID:
1756470
[Indexed for MEDLINE]
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