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J Clin Sleep Med. 2007 Feb 15;3(1):58-9.

Acute insomnia following surgery of the ventralis intermedius nucleus of the thalamus for tremor.

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  • 1Department of Neurology, University of Virginia, Charlottesville, VA 22908, USA.


Stereotactic surgery with lesioning or deep brain stimulation directed to the ventralis intermedius nucleus of the thalamus is a well-recognized treatment for medically intractable tremor. A patient developed the rare complication of severe insomnia, easy awakening, and lack of slow-wave sleep after thalamotomy/deep brain stimulation implantation. This complication underscores the role of thalamic regulation on initiation and maintenance of sleep.

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