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FEBS Lett. 2007 Jun 19;581(15):2870-6. Epub 2007 May 30.

The hard cell: from proteomics to a whole cell model.

Author information

1
Structural and Computational Biology Unit, European Molecular Biology Laboratory, Meyerhofstrasse 1, 69117 Heidelberg, Germany.

Abstract

Proteomics has provided a wealth of data related to the nature of the proteome, including subcellular location, copy number, interaction partners and protein complexes. This raises the question of whether it is feasible to combine these data, together with other data related to overall cellular structure, to construct a static picture of the cell. In this minireview, we discuss these data, and the issues of turning them into whole cell models.

PMID:
17555749
DOI:
10.1016/j.febslet.2007.05.062
[Indexed for MEDLINE]
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