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J Neurol Sci. 2007 Oct 15;261(1-2):84-8. Epub 2007 Jun 5.

The use of intraventricular thrombolytics in intraventricular hemorrhage.

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1
Neurology and Anesthesia Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore Maryland, 21287-7840, USA. pnyquis1@jhmi.edu

Abstract

Intraventricular hemorrhage (IVH) is associated with a high mortality and morbidity. Patients with this disorder may now be offered the possibility of treatment. This treatment comes in the form of intraventricular thrombolytics. At present a large randomized trial is testing the efficacy of intraventricular rt-PA in IVH in the setting of intracranial hemorrhage (ICH) . Preliminary data suggests that it may be successful in patients with IVH in this setting. This trial is the accumulation of animal and human trials completed over the last 20 years.

PMID:
17553525
DOI:
10.1016/j.jns.2007.04.039
[Indexed for MEDLINE]
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