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Curr Biol. 2007 Jun 5;17(11):R410-2.

Systems biology: a switch for sex.

Author information

1
Physical Biosciences Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, M.S. 977-152, Berkeley, California 94720, USA. ssandrews@lbl.gov <ssandrews@lbl.gov>

Abstract

The yeast pheromone response pathway works in a graded fashion, such that more pheromone leads to more response, but a recent study has shown that small modifications convert it into a bistable switch, with implications for the evolution and engineering of reaction networks.

PMID:
17550765
DOI:
10.1016/j.cub.2007.03.060
[Indexed for MEDLINE]
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