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J Clin Pediatr Dent. 2007 Spring;31(3):167-70.

The effectiveness of vitamin "E" in the treatment of oral mucositis in children receiving chemotherapy.

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Pediatric and Community Dentistry Department, Faculty of Dentistry, University of Alexandria, El-Ibrahimia, Alexandria, Egypt.


The aim of this study was to study the effect of vitamin "E" in the treatment of oral mucositis. 80 patients with oral mucositis were randomly distributed into 2 groups: group A, topically applied vitamin "E" and group B, vitamin "E" was given systemically. The 2 groups were evaluated for 5 days. Results showed that in group A grades of oral mucositis improved significantly, while in group B no significant improvement was noticed. It is concluded that topical application of 100 mg vitamin "E" twice daily is an effective measure for the treatment of chemotherapy-induced oral mucositis.

[Indexed for MEDLINE]

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