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Am J Obstet Gynecol. 2007 Jun;196(6):576.e1-6; discussion 576.e6-7.

Recurrence risk for preterm delivery.

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1
Department of Pediatrics, Division of Emergency Medicine, Washington University School of Medicine, St Louis, MO, USA.

Abstract

OBJECTIVE:

To estimate recurrence risk of preterm delivery in third births.

STUDY DESIGN:

We conducted a population-based cohort study of Missouri mothers who delivered 3 consecutive singleton live births during 1989-1997. The recurrence risk was computed for 4 cohorts based on prior preterm delivery status and adjusted using Mantel-Haenszel stratified analysis.

RESULTS:

The study population included 19,025 third births. The recurrence risk ranged from 42% (for women with 2 prior preterm deliveries), through 21% (term/preterm) and 13% (preterm/term), to 5% (term/term). The recurrence risk was highest (57%) for women with 2 prior very preterm deliveries (21-31 weeks) and lowest (33%) for those with 2 prior moderate preterm deliveries (32-36 weeks). The recurrence risk was less pronounced for women with 1 prior very or moderate preterm delivery.

CONCLUSION:

These data show a strong association between prior preterm delivery and recurrence risk, which is affected by the frequency, order, and severity of prior preterm births.

PMID:
17547902
DOI:
10.1016/j.ajog.2007.01.039
[Indexed for MEDLINE]
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