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Cornea. 2007 Jun;26(5):557-60.

Comparing central corneal thickness in a sub-Saharan cohort to African Americans and Afro-Caribbeans.

Author information

  • 1Manchester Royal Eye Hospital, Manchester, United Kingdom. doctormercieca@yahoo.com

Abstract

PURPOSE:

To evaluate the central corneal thickness (CCT) of Africans in a glaucoma practice in a university teaching hospital in West Nigeria, Africa, and compare results with similar studies carried out in African American and Afro-Caribbean populations.

METHODS:

CCT was measured by means of ultrasound pachymetry (pachymeter used was Micropach 200 P+ Pachymeter; Sonomed) in only African participants with either glaucomatous or healthy eyes. After instillation of topical anesthetic, 3 measurements of corneal thickness were taken, and the average thickness for each was calculated. The relationship between CCT and age was studied using correlation analyses and t tests. A total of 70 eyes were included for analysis.

RESULTS:

The mean CCT of all participants was 532.00 microm. Glaucoma suspects and patients with glaucoma had corneas thinner than those of normal participants (527.36 and 536.91 microm, respectively); however, the difference was not significant (P = 0.296). Decreasing values of CCT were significantly related to older age (P = 0.002). Men had a significantly higher CCT than women (P = 0.035).

CONCLUSIONS:

CCT values in African populations are less than those of whites. Decreasing values of CCT are significantly related to older age, and men have thicker corneas than women. There is a suggestion that CCT is lower in patients with glaucoma than in nonglaucomatous controls; however, the difference is not statistically significant. Comparing our results to other studies in literature, it seems that average CCT is similar between populations living in sub-Saharan Africa and African Americans and Afro-Caribbeans.

PMID:
17525651
DOI:
10.1097/ICO.0b013e3180415d90
[PubMed - indexed for MEDLINE]
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