Gastric linitis plastica metastatic to the uvea

Can J Ophthalmol. 1991 Oct;26(6):325-7.

Abstract

A 59-year-old man underwent total gastrectomy for diffuse, poorly differentiated gastric adenocarcinoma diagnosed as linitis plastica. Loss of vision in the right eye 5 months later due to extensive choroidal tumours was the first indication of metastatic disease. Radiologic studies showed multiple bony metastases. The blind, painful eye was enucleated. Pathological examination of the globe showed massive metastatic mucus-secreting adenocarcinoma of the choroid, with positive immunohistochemical staining for carcinoembryonic antigen (CEA) of the foci of the more highly differentiated neoplastic cells. The plasma CEA level had been normal. The patient died 3 months after enucleation from metastatic disease.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma / pathology
  • Adenocarcinoma / secondary
  • Adenocarcinoma / surgery
  • Eye Enucleation
  • Gastrectomy
  • Humans
  • Linitis Plastica / pathology
  • Linitis Plastica / secondary*
  • Linitis Plastica / surgery
  • Male
  • Middle Aged
  • Stomach Neoplasms / pathology*
  • Stomach Neoplasms / surgery
  • Uveal Neoplasms / pathology
  • Uveal Neoplasms / secondary*
  • Uveal Neoplasms / surgery