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Vis Neurosci. 1991 Oct;7(4):383-8.

Antibodies to human leucocyte antigens indicate subpopulations of microglia in human retina.

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1
Department of Ophthalmology, University of Sydney, Australia.

Abstract

Monoclonal antibodies to human leucocyte antigens, including anti-CD45 and anti-CD68, have been used to describe microglia in flatmounts of normal adult human retina for the first time. Anti-CD45 (the leucocyte common antigen) intensely labeled large numbers of cells in a regular distribution across the retina; anti-CD68 and anti-macrophage antibodies labeled fewer cells with distinctive morphologies, suggesting the presence of subpopulations of microglia in the human retina expressing leucocyte antigens.

PMID:
1751423
[Indexed for MEDLINE]
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