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Clin Biochem. 2007 Aug;40(12):913-5. Epub 2007 Apr 27.

Use of an interferon-gamma based assay to assess bladder cancer patients treated with intravesical BCG and exposed to tuberculosis.

Author information

1
University of Toronto, Ontario, Canada. msilverman@rogers.com

Abstract

OBJECTIVE:

Compare the QuantiFERON-TB Gold In-Tube (QFT) assay and the tuberculin skin test (TST) in bladder cancer patients receiving high dose BCG therapy (BCG patients).

DESIGN AND METHODS:

BCG patients and healthy visitors, both exposed to tuberculosis, were screened with a TST and QFT.

RESULTS:

QFT-TST correlation was excellent in visitors, but poor in BCG patients. BCG therapy predicted a positive TST (p<0.001) but not a positive QFT (p=0.35).

DISCUSSION:

The management of BCG patients was impacted, by measuring the QFT.

[Indexed for MEDLINE]

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