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Int J Radiat Oncol Biol Phys. 2007 Nov 1;69(3):671-6. Epub 2007 May 23.

Ultrasound-guided transrectal implantation of gold markers for prostate localization during external beam radiotherapy: complication rate and risk factors.

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1
Department of Urology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

Abstract

PURPOSE:

To report the complication rate and risk factors of transrectally implanted gold markers, used for prostate position verification and correction procedures.

METHODS AND MATERIALS:

In 209 consecutive men with localized prostate cancer, four gold markers (1 x 7 mm) were inserted under ultrasound guidance in an outpatient setting, and the toxicity was analyzed. All patients received a questionnaire regarding complications after marker implantation. The complications and risk factors were further evaluated by reviewing the medical charts.

RESULTS:

Of the 209 men, 13 (6.2%) had a moderate complication, consisting of pain and fever that resolved after treatment with oral medication. In 1.9% of the men, minor voiding complaints were observed. Other minor transient complications, defined as hematuria lasting >3 days, hematospermia, and rectal bleeding, occurred in 3.8%, 18.5%, and 9.1% of the patients, respectively. These complications were seen more often in patients with advanced tumor stage, younger age, and shorter duration of hormonal therapy.

CONCLUSION:

Transrectal gold marker implantation for high-precision prostate radiotherapy is a safe and well-tolerated procedure.

PMID:
17512133
DOI:
10.1016/j.ijrobp.2007.04.009
[Indexed for MEDLINE]
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