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Curr Opin Biotechnol. 2007 Jun;18(3):207-12. Epub 2007 May 16.

Mixed culture biotechnology for bioenergy production.

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Delft University of Technology, Department of Biotechnology, Julianalaan 67, 2628 BC Delft, The Netherlands.


Mixed culture biotechnology (MCB) could become an attractive addition or alternative to traditional pure culture based biotechnology for the production of chemicals and/or bioenergy. On the basis of ecological selection principles, MCB-based processes can be established that generate a narrow product spectrum from a mixed substrate. Three example processes are briefly discussed in this paper: anaerobic digestion aimed at the production of methane-containing biogas, mixed culture fermentation for the production of solvents or biohydrogen, and a two-step process for the production of polyhydroxyalkanoates. These examples give an idea of the potential contribution of mixed culture biotechnology to sustainable production of bioenergy from waste.

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