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Lancet Neurol. 2007 Jun;6(6):544-52.

Lyme neuroborreliosis: infection, immunity, and inflammation.

Author information

1
Department of Neurosciences, UMDNJ-New Jersey Medical School, Newark, NJ 07103, USA. pachner@umdnj.edu

Abstract

Lyme neuroborreliosis (LNB), the neurological manifestation of systemic infection with the complex spirochaete Borrelia burgdorferi, can pose a challenge for practising neurologists. This Review is a summary of clinical presentation, diagnosis, and therapy, as well as of recent advances in our understanding of LNB. Many new insights have been gained through work in experimental models of the disease. An appreciation of the genetic heterogeneity of the causative pathogen has helped clinicians in their understanding of the diverse presentations of LNB.

PMID:
17509489
DOI:
10.1016/S1474-4422(07)70128-X
[Indexed for MEDLINE]

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