[Narrow band UVB therapy in early stage mycosis fungoides. A study of 23 patients]

Actas Dermosifiliogr. 2007 May;98(4):259-64.
[Article in Spanish]

Abstract

Introduction: Phototherapy is effective for mycosis fungoides. Narrow band UVB (UVB1) therapy is being used as an alternative to PUVA therapy for its efficacy and less adverse events. The objective of the study was to determine the efficacy of narrow band UVB therapy in early stage mycosis fungoides.

Methods: It is a retrospective study of 23 patients with stage IB mycosis fungoides that have received UVB1 therapy following the phototherapy protocol of the Spanish Photobiology Group.

Results: Thirteen patients (57 %) had a complete response, eight patients (35 %) had a partial response and two patients (8 %) did not respond. Half of the patients with complete response (n = 6) relapsed after one year of follow-up.

Conclusions: We consider that UVB1 therapy is a good alternative for treatment of early stage mycosis fungoides, although the disease-free period is short.

Publication types

  • Evaluation Study

MeSH terms

  • Adult
  • Aged
  • Female
  • Humans
  • Male
  • Middle Aged
  • Mycosis Fungoides / pathology
  • Mycosis Fungoides / radiotherapy*
  • Neoplasm Recurrence, Local
  • Neoplasm Staging
  • Remission Induction
  • Retrospective Studies
  • Skin Neoplasms / pathology
  • Skin Neoplasms / radiotherapy*
  • Treatment Outcome
  • Ultraviolet Therapy / methods*