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J Am Acad Dermatol. 2007 Jul;57(1):81-3. Epub 2007 May 10.

Adherence to topical therapy increases around the time of office visits.

Author information

1
Center for Dermatology Research, Department of Dermatology, The Ohio State University College of Pharmacy, Columbus, USA. sfeldman@wfubmc.edu

Abstract

BACKGROUND:

The efficacy of topical medications is limited by non-adherence. Interventions to improve adherence to topical treatments are not well characterized.

OBJECTIVE:

To assess the impact of office visits on patients' adherence to topical treatment.

METHODS:

Twenty-nine subjects enrolled in a clinical trial for psoriasis and were followed for up to 8 weeks. Subjects were told to apply 6% salicylic acid gel twice daily. Electronic monitors were used to assess adherence. Results were compared to adherence in clinical trials of hand dermatitis and atopic dermatitis.

RESULTS:

Adherence rates were significantly higher around the time of office visits (P < .05).

LIMITATIONS:

This is a small study in a limited patient population. The study was observational and not a randomized trial of the effect of increased office visits.

CONCLUSION:

Frequent follow-up visits in clinical trials increase patients' adherence to medications. The use of a follow-up visit shortly after initiating treatment may be an effective way to boost patients' use of their medication and achieve better treatment outcomes.

PMID:
17498841
DOI:
10.1016/j.jaad.2007.04.005
[Indexed for MEDLINE]
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