Format

Send to

Choose Destination
See comment in PubMed Commons below
Surg Clin North Am. 2007 Apr;87(2):365-77, ix.

Axillary management after sentinel lymph node biopsy in breast cancer patients.

Author information

1
Lynn Sage Comprehensive Breast Center/Northwestern University, 675 North St. Clair Street, Galter 13-174, Chicago, IL 60611, USA.

Abstract

According to the available data, sentinel lymph node (SLN) biopsy is proving to be an accurate staging technique with less post-surgical morbidity than standard axillary lymph node dissection (ALND). Survival benefits associated with SLN biopsy and, as well as the significance of IHC detected micrometastases have yet to be determined. The long term results of several multicenter trials are pending, yet preliminary results are in favor of abandoning ALND in favor of the less invasive alternative. Despite this, ALND remains the standard of care in breast cancer patients with clinically palpable axillary lymph nodes that are suspicious for metastatic disease. Although controversial, many clinicians believe that axillary metastases will precede systemic spread of disease. Therefore, axillary clearance of clinically palpable nodes could potentially quell the progression of metastases. Regardless of whether or not this theory is true, not many would argue against debulking suspicious nodal disease.

PMID:
17498532
DOI:
10.1016/j.suc.2007.01.014
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center