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Cell. 2007 May 4;129(3):459-60.

BDNF instructs the kinase LKB1 to grow an axon.

Author information

1
Department of Neuroscience, University of Virginia Medical School, Charlottesville, VA 22908, USA. bwinckler@virginia.edu <bwinckler@virginia.edu>

Abstract

Determining which neurite of a differentiating neuron is to become the axon is a crucial step in neuronal morphogenesis. Two groups (Barnes et al., 2007; Shelly et al., 2007) now report that axon specification in vivo is mediated by extracellular signals acting through the serine/threonine kinase LKB1.

PMID:
17482540
DOI:
10.1016/j.cell.2007.04.021
[Indexed for MEDLINE]
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