Format

Send to

Choose Destination
See comment in PubMed Commons below
Anal Bioanal Chem. 2007 Aug;388(7):1381-91. Epub 2007 Apr 28.

Recent developments in extraction procedures relevant to analytical toxicology.

Author information

1
Laboratory of Toxicology, Ghent University, Harelbekestraat 72, 9000 Gent, Belgium.

Abstract

Sample preparation is an important step in the development of an analytical method but is often regarded as time-consuming, laborious work. Optimum sample preparation leads to enhanced selectivity and sensitivity, however, and reduces amounts of interfering matrix compounds, resulting in less signal suppression or enhancement. Recent developments in extraction techniques that could be of interest in clinical and forensic toxicology, for example liquid-liquid, solid-phase, and headspace extraction, are summarized in this review. The advantages and disadvantages of several extraction techniques are discussed, to enable the reader to choose an appropriate method of extraction for his or her application. Attention is paid to current trends in analytical toxicology, for example miniaturization, high throughput, and automation.

PMID:
17468854
DOI:
10.1007/s00216-007-1294-z
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Springer
    Loading ...
    Support Center