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Rev Mal Respir. 2007 Apr;24(4 Pt 1):535-51.

[Respiratory manifestations during the course of Sjogren's syndrome].

[Article in French]

Author information

1
Service de Pneumologie A, APHP, Hôpital Bichat, Paris, France. bruno.crestani@bch.aphp.fr

Abstract

INTRODUCTION:

Sjogren's syndrome is a common auto-immune disease.

BACKGROUND:

Clinically significant pulmonary involvement affects approximately 10% of patients and may be the first manifestation of the disease, putting the respiratory physician in a position to suspect and confirm the diagnosis. Besides interstitial lung disease and bronchial disorders, cough is a common symptom of the disease and particularly difficult to treat. Lung cysts and amyloid deposits, sometimes associated with lymphoma, have recently been described. The development of a primary pulmonary lymphoma, usually from MALT, is a major complication of the disease.

VIEWPOINT:

Characterisation of the pathophysiology of pulmonary involvement in Sjogren's syndrome and the institution of specific treatment merits the interest of the respiratory physician.

CONCLUSION:

The respiratory physician should consider the diagnosis of Sjogren's syndrome in many different clinico-pathological situations.

PMID:
17468709
[Indexed for MEDLINE]
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