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Carbohydr Res. 2007 Sep 3;342(12-13):1974-82. Epub 2007 Mar 28.

The solution conformation of C-glycosyl analogues of the sialyl-Tn antigen.

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1
Centro de Investigaciones Biológicas, CSIC, Ramiro de Maeztu 9, 28040 Madrid, Spain.

Abstract

The conformational behavior of two C-glycosyl analogues of the sialyl-Tn antigen has been determined by a combination of NMR methods and molecular mechanics calculations. Both compounds show a major solution conformation that is drastically different from the major one of the natural compound.

PMID:
17466287
DOI:
10.1016/j.carres.2007.03.021
[Indexed for MEDLINE]
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