Powered hand tools produce reaction forces that may be associated with upper extremity musculoskeletal disorders. The handle displacement, grip force and upper limb muscle activity (electromyography (EMG)) due to the effects of operator experience, working height and distance, type of tool and fastener joint hardness were measured in this study with 15 experienced and 15 novice nutrunner users. The results show that when pistol grip handles were used to work on a horizontal surface, experienced users allowed an average handle displacement of 7.9 degrees, while novice users allowed 11.5 degrees. Average EMG scaled by reference voluntary contraction (RVC) at forearm flexors, forearm extensors and biceps were greater for experienced users (318% RVC, 285% RVC, 143% RVC, respectively) than for novice users (246% RVC, 219% RVC, 113% RVC, respectively). Experienced users exerted more grip force than novice users when using right angle handles, but less force when using pistol grip handles. The results suggest that it is possible to minimize tool handle displacement by adapting the workplace layout to permit different working postures for each user group.