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Chem Commun (Camb). 2007 May 7;(17):1713-5. Epub 2007 Apr 3.

Genotoxicity screening for N-nitroso compounds. Electrochemical and electrochemiluminescent detection of human enzyme-generated DNA damage from N-nitrosopyrrolidine.

Author information

1
Department of Chemistry (U-60), 55 N. Eagleville Rd., University of Connecticut, Connecticut, USA.

Abstract

We report for the first time voltammetric/electrochemiluminescent sensors applied to predict genotoxicity of N-nitroso compounds bioactivated by human cytochrome P450 enzymes.

PMID:
17457417
DOI:
10.1039/b703012f
[Indexed for MEDLINE]

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