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Appl Environ Microbiol. 2007 Jun;73(11):3765-7. Epub 2007 Apr 20.

Shedding of Escherichia coli O157:H7 in calves is reduced by prior colonization with the homologous strain.

Author information

1
Animal Health Group, Scottish Agricultural College, Edinburgh EH9 3JG, UK. stuart.naylor@sac.ac.uk

Abstract

Enterohemorrhagic Escherichia coli O157:H7 has a natural reservoir in the intestinal tracts of cattle. Colonization is asymptomatic and transient, but it is not clear if protective immunity is induced. This study demonstrates that prior colonization induces humoral immune responses to bacterial antigens and reduces bacterial shedding after experimental challenge with the homologous strain.

PMID:
17449700
PMCID:
PMC1932681
DOI:
10.1128/AEM.02670-06
[Indexed for MEDLINE]
Free PMC Article

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