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Bioorg Med Chem Lett. 2007 May 15;17(10):2944-8. Epub 2006 Dec 21.

Bridged androstenediol analogs as ER-beta selective SERMs.

Author information

1
Merck Research Laboratories, PO Box 2000, Rahway, NJ 07065, USA. tim_blizzard@merck.com

Abstract

A series of bridged androstenediol derivatives was prepared. The bridged compounds exhibited reduced ER-beta selectivity relative to uncyclized analogs.

PMID:
17448656
DOI:
10.1016/j.bmcl.2006.12.053
[Indexed for MEDLINE]

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