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Zhejiang Da Xue Xue Bao Yi Xue Ban. 2007 Mar;36(2):199-203.

[Carnosine and diseases of central nervous system].

[Article in Chinese]

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Department of Pharmacology, College of Medicine, Zhejiang University, Hangzhou 310058, China.


The naturally-occurring dipeptide carnosine (beta-alanyl-L-histidine) is found exclusively in animal tissues, such as brain and skeletal muscle tissues. Carnosine is a potent hydrophilic antioxidant, antiglycating agent, reactive oxygen species scavenger and pH-buffer. Recent reports suggest that carnosine has potential therapeutic applications in many diseases of central nervous system, such as Alzheimer's disease, Parkinson's disease and cerebral ischemic diseases. To investigate the relationship between carnosine and diseases of central nervous system, and to research and develop carnosine drugs will shed light on a new way for treatment of diseases of central nervous system.

[Indexed for MEDLINE]

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