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Eur J Neurol. 2007 May;14(5):591-3.

White matter changes in Leber's hereditary optic neuropathy: MRI findings.

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Department of Neuroradiology, The Radcliffe Infirmary, Oxford, UK.


Leber's hereditary optic neuropathy is a mitochondrial disorder causing bilateral optic nerve degeneration. It is sometimes associated with clinical signs of multiple sclerosis. We report MRI findings in two patients with LHON-MS and comment on possible distinguishing features of this disease entity.

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